Ganglioglioma: a Medically Intractable cause of Epilepsy
Winston Cárdenas-Chávez; Eileen Cortecero-Sabalza ; Yancarlos Ramos-Villegas; Loraine Quintana-Pájaro; Alfonso I. Pacheco-Hernández; Luis Rafael Moscote-Salazar
Abstract
Introduction: Gangliogliomas are very rare benign primary tumors of the central nervous system with mixed histological characteristics, generally located in the temporal lobe. They represent 40% of epileptogenic tumors. They mainly affect children, adolescents, and young adults. They have a good prognosis if complete resection of the lesion is achieved. Clinical case: A 15-year-old patient who presented with seizures for four years that began with headaches followed by generalized tonic-clonic movements accompanied by automatisms, of short duration, without relaxation of the sphincters and postictal with drowsiness for ten minutes. Discussion: Neoplasms of the central nervous system can be primary or secondary. Each tumor has its particular characteristics. The prognosis of these patients depends significantly on the location and growth pattern of the lesion. Gangliogliomas are rare tumors of the central nervous system that most frequently affect people in the first three decades of life. The diagnosis is obtained from neuroimaging and histopathology. The treatment of choice is surgery, removing the entire lesion, which leads to good symptomatic control. Adjuvant treatment with chemotherapy and radiotherapy is usually not necessary.
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References
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Submitted date:
12/01/2022
Reviewed date:
12/14/2022
Accepted date:
12/23/2022